教师名录
陈华英
通讯地址:深圳市南山区西丽大学城哈工大校区D栋207室
电子邮件:chenhuaying@hit.edu.cn
联系电话:+86 755 8615 3249

个人简介

陈华英博士在本科和硕士期间从事材料方面的学习和研究。自攻读博士学位起,他一直致力于微流控芯片的开发和应用研究。他的主要成果包括:一、微流体芯片和微器件(包括微泵、微阀门及微电极)的设计与加工研究;二、流体力学和计算流体力学的研究;三、微流体芯片在细胞分析、病原体和生物标记检测以及胚胎筛选方面的应用。

***诚聘博士后***
招聘微流控芯片和细胞分析方向博士后1名,具有微流控芯片、细胞生物学或微纳制造研究背景(符合任意一条即可)的可以优先考虑。详情请打电话或发邮件咨询。

***欢迎报考硕士研究生***
陈华英老师从哈尔滨工业大学(深圳)理学院力学方向招生。欢迎有流体力学、生物工程、机械或材料背景及兴趣的同学联系报考硕士研究生。

研究方向

一、基于纸芯片的即时检测(Point of care testing based on paper microfluidics)
二、基于芯片实验室装置的细胞分析 (Lab on a chip for cell analysis)
三、微尺度流体力学 (Micro Fluid Mechanics)

教育经历

2008-2012  澳大利亚新南威尔士大学 博士
2006-2008  山东大学材料科学与工程学院 硕士研究生
2000-2004  山东大学材料科学与工程学院 本科

研究与工作经历

2016-  哈尔滨工业大学(深圳)机电工程与自动化学院 副教授
2014-2016  澳大利亚联邦科学与工业研究组织 博士后
2012-2014   澳大利亚昆士兰大学 澳大利亚生物工程与纳米技术研究所 博士后
2004-2006  山东大学材料科学与工程学院 辅导员

专业资质与学术兼职

2012  澳大利亚工程师协会材料工程师
2017  深圳市微米纳米技术学会 理事

科研项目

2018-2020  国家自然科学基金青年项目:单细胞筛选和回收机理及干细胞克隆扩增动力学研究(主持,26万元)
2017-2020  深圳市启动项目:面向单个干细胞研究的微流控芯片平台研发(主持,300万元)
2016-2019  哈工大(深圳)新教师科研启动项目:单个微球在磁性阵列和微流中的高通量捕获研究(主持)
2018-2019  哈尔滨工业大学科研创新基金:单个细胞乳酸盐释放量长期、精密测量技术研究(主持)
2018-2019  深圳市基础研究自由探索项目:面向液体活检和个性化医疗的单个循环肿瘤细胞筛选芯片的研发(主持,50万元)
2019-2020  深圳市基础研究自由探索项目:用于药物筛选和个性化医疗的血栓芯片的研发(主持,50万元)

科研成果及奖励

  
2017  深圳市南山区领航人才C类

发明专利

1)陈华英、朱永刚、陈畅。一种集成单细胞捕获与筛选功能的微流控芯片与筛选方法。国家发明专利,申请号:201810031792.7,申请日期:2018年1月12日。
2)陈华英、朱永刚、陈畅。一种集成单细胞捕获与筛选功能的微流控芯片。实用新型专利,申请号:201820058155.4,申请日期:2018年1月12日。
3)陈华英、陈畅、朱永刚、于志航。一种流体剪切力生成装置与流体剪切力生成方法。国家发明专利,申请号:201810228424.1,申请日期:2018年3月20日。
4)陈华英、陈畅、朱永刚、于志航。一种流体剪切力生成装置。实用新型专利,申请号:201820375972.2,申请日期:2018年3月20日。

论文及著作

(1) Huaying Chen*, Zhihang Yu, Siwei Bai, Huaxiu Lu, Dong Xu, Chang Chen, Di Liu, Yonggang Zhu. Microfluidic models of physiological or pathological flow shear stress for cell biology, disease modeling and drug development. Trends in Analytical Chemistry, 2019. (JCR 一区,影响因子:8.428)
(2) Chang Chen, Litao Zhao, Han Zhang, Xiaoshuang Shen, Yonggang Zhu and Huaying Chen*. Novel wax valves to improve distance-based analyte quantification in paper microfluidics. Analytical Chemistry, 2019. (JCR 一区,影响因子:6.35)
(3) Huaying Chen, Chang Chen, Siwei Bai, Yuan Gao, Guy Metcalfe, Wenlong Cheng and Yonggang Zhu*. Multiplexed detection of cancer biomarkers using a microfluidic platform integrating single bead trapping and acoustic mixing techniques. Nanoscale, 2018,43.(JCR 一区,影响因子:6.970)
(4) Huaying Chen, Yuan Gao, Petkovic Karolina, Yan Sheng, Best Michael, Yanping Du and Yonggang Zhu*, Reproducible bubble-induced acoustic microstreaming for bead disaggregation and immunoassay in microfluidics. Microfluidics and Nanofluidics, 2017,21(3):30.(JCR 二区,2.437)
(5) Huaying Chen, Jane Sun, Ernst J. Wolvtang and Justin J. Cooper-White*, High-throughput, deterministic single cell trapping and long-term cell culture in microfluidic devices, Lab On a Chip, 2015, 15, 1072–1083.(JCR 一区,影响因子:6.914)
(6) Huaying Chen, James Cornwell, Han Zhang, Tse Lim, Rena Resurreccion, Timothy Port, Gary Rosengarten, and Robert E Nordon*, Cardiac-like flow generator for long-term imaging of endothelial cell responses to circulatory pulsatile flow at microscale, Lab On a Chip, 2013, 13 15: 2999-3007. (JCR 一区,影响因子:6.914)
(7) Huaying Chen, Gary Rosengarten, Musen Li, and Robert E. Nordon*, Design of microdevices for long-term live cell imaging, Journal of Micromechanics and Microengineering, 2012, 22 6: 065033.1-065033.10. (JCR 二区,影响因子:2.141)
(8) Huaying Chen, Jingjing Li, Han Zhang, Musen Li, Gary Rosengarten, and Robert E. Nordon*, Microwell perfusion array for high-throughput, long-term imaging of clonal growth. Biomicrofluidics, 2011, 5 4: 044117.1-044117.12. (JCR 二区,影响因子:2.571)
(9) Jiaming Shi, Lei Tong, Wenqiang Tong, Huaying Chen, Minbo Lan, Xiaoxi Sun and Yonggang Zhu*. Current progress in long-term and continuous cell metabolite detection using microfluidics. Trends in Analytical Chemistry. 2019. (JCR一区,影响因子:8.428)
(10) Lim Wei Yap, Huaying Chen, Yuan Gao, Karolina Petkovic, Yan Liang, Kae Jye Si, Huanting Wang, Zhiyong Tang, Yonggang Zhu and Wenlong Cheng*. Bifunctional plasmonic-magnetic particles for an enhanced microfluidic SERS immunoassay. Nanoscale. 2017;9(23), 7822-7829.(JCR 一区,影响因子:6.970)
(11) Karolina Petkovic, Guy Metcalfe, Huaying Chen, Yuan Gao, Michael Best, D. Lester and Yonggang Zhu*, Rapid Detection of Hendra Virus Antibodies: An Integrated Device with Nanoparticle Assay and Chaotic Micromixing, Lab on a chip ,2016. (JCR 一区,影响因子:6.914)
(12) Yanping Du, Nam Le, Dong Chen, Huaying Chen and Yonggang Zhu*, Thermal management of solar cells using a nanocoated heat pipe plate: an indoor experimental study, International Journal of Energy Research ,2016. (JCR 一区,影响因子:3.343)
(13) Huihui Yuan, Bin Qian, Huaying Chen and Minbo Lan*, The influence of conditioning film on antifouling properties of the polyurethane film modified by chondroitin sulfate in urine. Applied Surface Science 426, 587-596, doi:10.1016/j.apsusc.2017.06.314 (2017). (JCR 一区,影响因子:5.155)
(14) Huihui Yuan, Jing Xue, Bin Qian, Huaying Chen, Yonggang Zhu and Minbo Lan*, Preparation and antifouling property of polyurethane film modified by chondroitin sulfate, Applied Surface Science, 2017, 394, 403-413. (JCR 一区,影响因子:5.155)
(15) Sheng Yan, Jun Zhang, Huaying Chen, Dan Yuan, GurselAlici, Haiping Du, Yonggang Zhu, and Weihua Li*, Development of a novel magnetophoresis-assisted hydrophoresis microdevice for rapid particle ordering, Biomedical Microdevices,2016,18,1-9. (JCR 二区,影响因子:2.327)
(16) Gleb E. Yakubov, Mauricio R. Bonilla, Huaying Chen, Monika S. Doblin, Antony Bacic, Michael J. Gidley and Jason R. Stokes *, Mapping nano-scale mechanical heterogeneity of primary plant cell walls, Journal of Experimental Botany, 2016, 67(9):2799-2816. (JCR 一区,影响因子:5.36)
(17) Sheng Yan, Jun Zhang, Huaying Chen, Gursel Alici, Haiping Du, Yonggang Zhu, Weihua Li*, Making a hydrophoretic focuser tunable using a diaphragm, Biomicrofluidics, 2015, 8(6):064115. (JCR 二区,影响因子:2.571)
(18) Drew M. Titmarsh, Huaying Chen, Nick R. Glass and Justin J. Cooper-White*, Microfluidic technology platforms: poised to accelerate development and translation of stem cell-derived therapies, STEM CELLS Translational Medicine, 2014, 3(1):81-90. (JCR 一区,影响因子:4.11)
(19) Drew M. Titmarsh, Huaying Chen, Ernst J. Wolvetang and Justin J. Cooper-White*, Arrayed cellular environments for stem cells and regenerative medicine, Biotechnology Journal, 2013,8 2: 167-179. (JCR 二区,影响因子:3.543)




会议论文及发表演说

会议论文
[1] Chen, H., G. Rosengarten, and R. Nordon, Statistical Analysis of Cellular Retention by Micro-well Arrays. 2010.
[2] Chen, H., K. Petkovic-Duran, M. Best, and Y. Zhu. Bubble-induced acoustic mixing in a microfluidic device. in SPIE Micro+Nano Materials, Devices, and Systems. 2015. Sydney: SPIE.
会议报告
[1] 2016 International Conference of Microfluidics, Nanofluidics and Lab-on-a-Chip, 10-12 June, 2016. Dalian, China. Multiplexed biomarker detection using a microfluidic platform integrating single bead trapping and acoustic mixing. Huaying Chen, Yuan Gao, Karolina Petkovic, Michael Best, Vicky Boyd and Yonggang Zhu (Presenter).
[2] The 40th Annual Australasian Chemical and Process Engineering Conference, 26 - 29 September 2010, Hilton Hotel, Adelaide, Australia. Title: Statistical Analysis of Cellular Retention by Micro-well Arrays.
[3] BIT's 3rd Annual Congress of Regenerative Medicine & Stem Cell-2010, 5-7 December 2010, Shanghai China. Title: Micro-well Array Perfusion Bioreactor for High-throughput Lineage Analysis.
[4] OCE cutting edge symposium on Lab on a chip sensing platforms 17-18 July 2014, Melbourne, Australia. Title: High-throughput, deterministic single cell trapping and clonal culture in microfluidics.
[5] The 6th Australia and New Zealand Nano Microfluidics Symposium, 31 March-2 April 2015, Melbourne, Australia. Title: Development of a microfluidic platform for ‘one pot’ detection of pathogens.
[6] SPIE Micro+Nano Materials, Devices, and Systems, 6-9 December 2015. Sydney, Australia. Title: Bubble-induced acoustic mixing in a microfluidic device.
[7] The 7th Australia and New Zealand Nano Microfluidics Symposium, 21-23 March 2016, Brisbane, Australia. Title: Multiplexed biomarker detection using a microfluidic platform integrating single bead trapping and acoustic mixing.
[8] 20th Australasian Fluid Mechanics Conference (20AFMC). 5-8 December 2016. Perth, Australia. Title: Trapping of single magnetic beads in a micro flow (Accepted).

任教和任导师经历

主讲研究生课程《微纳尺度流体力学》  学位课
学时:32
开课时间:秋季
主讲本科生课程《机械工程材料及成形技术》  学时:24
开课时间:秋季
最后更新:2019-07-14 16:01:18